Substituted quinoxalines are known building blocks for compounds with pharmacological, agricultural, and material uses.Forming carbon-heteroatom bonds at the 2,3-positions on quinoxaline can be challenging.2,3-chloroquinoxaline can undergo nucleophilic aromatic substitution however it must be 3 Pc. Sectional w/ Ottoman Package in the presence of metal catalysts.
A range of nucleophiles are investigated to showcase the broad EVERYONE LOTION LAVENDER range of potential substitution partners that can be incorporated effectively into the 2,3-disubstituted scaffold.This research focuses on a robust microwave-assisted one-pot procedure to gain efficient access to symmetrically 2,3-substituted quinoxalines without the use of a metal catalyst.